The post is intended for an applicant within any of these three specialities, with the speciality of the final (single) post dependent on the successful applicant.

The post-holder will be pursuing their development of research and teaching within either the Primary Care, Population Science and Medical Education school, Human Development and Health school or Clinical and Experimental Sciences school of the Faculty of Medicine, University of Southampton.  

In this post-doctoral role, the successful candidate will be in specialist clinical training at ST3 level or above and have substantial experience of the relevant research areas, a proven track record of high-quality original research publications, the ability to work well in a multidisciplinary, multi-professional team and hold a corresponding NTN.

You will join the NIHR Clinical Integrated Academic Training Programme at the University of Southampton, as an NIHR Academic Clinical Lecturer. The post-holder will also have clinical commitments at University Hospital Southampton NHS Foundation Trust that will lead to the acquisition of clinical skills required for full registration within the specialty.

The post is subject to terms and conditions of service determined by the University of Southampton and in its honorary clinical capacity by the University Hospital Southampton Foundation Trust Board.

Informal enquiries are welcome and should be addressed to: 

Public Health: Professor Simon Fraser, Professor of Public Health - email: s.fraser@soton.ac.uk

Paediatrics: Professor Graham Roberts, Professor of Paediatric Allergy & Respiratory Medicine - email: g.c.roberts@soton.ac.uk

Ophthalmology: Professor Andrew Lotery, Professor of Ophthalmology - email: a.j.lotery@soton.ac.uk

A satisfactory Criminal Records Bureau disclosure at Enhanced level is required for this post.

Please note: successful applicants will be appointed to a different salary range (AMNL £46,675 to £80,081) if they were at ST3 on or before 2 August 2016. 

The Faculty of Medicine holds an Athena SWAN Silver Award demonstrating commitment to equal opportunities and gender balance in the workplace. The Faculty recognises that applicants may seek flexible working patterns which will be considered as part of the recruitment process. For further information including key benefits designed to help maintain and support employees' well-being and work-life balance, please see our working with us website pages.

Closing Date: 21 May 2026

Section: Clinical

Salary: £65,048 to £73,992 per annum
Full Time Fixed Term for 4 years (up to 6 years part-time)

The post is intended for an applicant within any of these three specialities, with the speciality of the final (single) post dependent on the successful applicant. 

The post-holder will be pursuing their development of research and teaching within the Faculty of Medicine, University of Southampton. 

In this post-doctoral role, the successful candidate will be in specialist clinical training at ST3 level or above and have substantial experience of the relevant research areas, a proven track record of high-quality original research publications, the ability to work well in a multidisciplinary, multi-professional team and hold a corresponding NTN. 

You will join the NIHR Clinical Integrated Academic Training Programme at the University of Southampton, as an NIHR Academic Clinical Lecturer. The post-holder will also have clinical commitments at University Hospital Southampton NHS Foundation Trust that will lead to the acquisition of clinical skills required for full registration within the specialty.

The post is subject to terms and conditions of service determined by the University of Southampton and in its honorary clinical capacity by the University Hospital Southampton Foundation Trust Board.

Informal enquiries are welcome and should be addressed to: 

Paediatrics, Professor Graham Roberts, Professor of Paediatric Allergy & Respiratory Medicine email: g.c.roberts@soton.ac.uk 

Ophthalmology, Professor Andrew Lotery, Professor of Ophthalmology, email: a.j.lotery@soton.ac.uk

Respiratory Medicine, Professor Mark Jones, Professor of Respiratory Medicine email: mark.jones@soton.ac.uk 

A satisfactory Criminal Records Bureau disclosure at Enhanced level is required for this post. 

Please note: successful applicants will be appointed to a different salary range (AMNL £46,675 to £80,081) for those below ST3 on 3 August 2016; (CADT £65,048 to £73,992) for those at or above ST3 on 3 August 2016.

The Faculty of Medicine holds an Athena SWAN Silver Award demonstrating commitment to equal opportunities and gender balance in the workplace. The Faculty recognises that applicants may seek flexible working patterns which will be considered as part of the recruitment process. For further information including key benefits designed to help maintain and support employees' well-being and work-life balance, please see our working with us website pages.

Closing Date: 22 May 2026

Section: Clinical

Salary: £65,048 to £80,081 per annum
Full Time Fixed Term (4 years full-time, up to 6 years part-time)

You should have extensive laboratory expertise in cell biology and human tissue culture. The role includes extensive work with human pluripotent stem cells and so previous experience and expertise with CRISPR/Cas9 technologies in addition to laboratory leadership would be an advantage. For example some work will include reprogramming hiPSC derived from patient fibroblasts and retinal organoid cultures. You should be a highly motivated candidate, capable of independently designing and carrying out experiments as well as intellectually contributing to the projects and managing multiple workstreams to achieve their goals in a timely manner. You should be interested in the interface between lab-based research and clinical research and ideally have a track record of publishing in high-quality, peer-reviewed journals.

The vision group investigates various aspects of paediatric and adult eye disease from very clinical projects to lab based and genetic studies in-house with multiple collaborations between PI’s in the vision research group. This role is to support those aspects of projects related to stem cell work. Importantly, this includes regular but minimal weekend maintenance work and covering other staff duties where necessary. Hence, this exciting role offers the opportunity to work at the interphase of cutting-edge, multidisciplinary research on multiple ophthalmic disorders. You will join a vibrant and dynamic research group and be expected to work as a team with other postdocs, PhD/undergraduate students, clinician scientists and technicians as part of the wider vision research group. You will collaborate with colleagues across Faculties of Medicine and Biological Sciences at the University of Southampton and colleagues in other institutions. The candidate can expect a collegial and research-focused environment with mentoring and career development support from the line manager Jorn Lakowski and the other vision groups PI team. 

The post is available for a period of 2 years in the first instance. Interviews for shortlisted candidates are likely to be held in March/April 2026. Informal inquires may be directed to Dr. Jorn Lakowski (J.Lakowski@soton.ac.uk). 

Closing Date: 28 Apr 2026

Section: Technical & Experimental

Salary: £31,236 to £35,608
Full Time Fixed Term (2 Years)

An exciting opportunity is available to join the laboratories of Dr Ali Roghanian and Dr Salah Mansour at the University of Southampton in collaboration with MiNK Therapeutics. We are seeking a collaborative and motivated scientist to work on our newly funded programme developing next-generation, off-the-shelf immunotherapies for childhood cancers.

This 12 month project will harness engineered cytotoxic invariant Natural Killer T (iNKT) cells for precision targeting of paediatric cancer neoantigens. Building on strong preliminary data, it combines mechanistic and translational immunology with bespoke preclinical models to define and exploit therapeutic candidates. The Research Technician will lead studies on cytotoxic T cell mechanisms, oversee preclinical validation, and advance TCR-engineered iNKT platforms optimised for immunotherapy.

The role bridges basic and translational research and suits a creative scientist with interests in tumour immunology, T cell engineering, and immunotherapy. You will join a multidisciplinary team spanning immunology, with access to advanced flow cytometry and in vivo platforms.

The funding is initially available for 12 months, with the possibility of extension to 21 months, subject to satisfactory progress.

Key responsibilities

• To work within the Mansour and Roghanian labs, and with collaborators at Southampton, LifeArc and MiNK Therapeutics.
• To design, conduct, and analyse in vitro immunology experiments.
• To lead the optimisation and functional assessment of engineered human T cells.
• To liaise and coordinate between project collaborators, including the industrial partner, and core facilities.
• To record analyses accurately and present results at group and collaborative meetings, and conferences.
• To contribute to dissemination of findings through publications and grant applications.
• Any other duties appropriate to the scope and grade of the post.

Essential qualifications, experience and competencies

• Degree (BSc or equivalent) in biological or biomedical sciences or equivalent experience
• Strong practical experience with core immunological assays (e.g., FACS, ELISA, T cell assays).
• Ability to manage projects to timelines, and work both independently and collaboratively.
• Excellent communication and presentation skills, including at conferences.

Desirable

• Experience in engineering human T cells, viral transduction, or related approaches.

About us

The University of Southampton offers a strong environment for translational immunology. Clinical and Experimental Sciences (CES) is a hub for infection and immunology, while the Centre for Cancer Immunology (CCI) is the UK’s first dedicated cancer immunology centre. Together, they unite expertise in T cell biology, multiomics, immunotherapy, preclinical modelling, and clinical translation, supported by an embedded Clinical Trials Unit and close links with NHS and industry partners.

Application

Applicants should provide:

• A CV
• A cover letter outlining suitability for the role
• Contact details for at least two recent referees

Start date: May 2026 or soon after (negotiable)

Closing Date: 26 Apr 2026

Section: Technical & Experimental

Salary: £36,636 to £37,694 per annum
Full Time Fixed Term for 12 months