The successful candidate will be responsible for designing, implementing, and maintaining Microsoft Azure-based infrastructure, ensuring that the SDE meets stringent security, governance, and compliance requirements associated with clinical research. The role requires experience with cloud platforms, infrastructure as code, and modern DevOps practices, alongside an understanding of networking, monitoring, and system reliability. Experience or interest in the clinical trials or healthcare domain, including the use of informatics and IT to support research, will be highly beneficial.

This position offers the opportunity to contribute to innovative projects in medical research while working in a collaborative and supportive environment. The ideal candidate will demonstrate initiative, creativity, and a genuine interest in applying technology to improve healthcare outcomes, along with strong problem-solving skills and the ability to work both independently and as part of a team.

The University of Southampton offers excellent career development and training opportunities as well as a generous holiday allowance (30 days) including bank holidays (8 days) and paid closure days (6 days). 

The University of Southampton gives you access to a wide range of benefits in addition to our competitive rates of pay and pension scheme membership and excellent family leave arrangements. 

If you would like to discuss the job with a member of the CIRU team please contact Lawrence Surey on ciru@soton.ac.uk

Closing Date: 13 May 2026

Section: Management, Specialist & Administrative

Salary: £36,636 to £44,746 per annum
Full Time Fixed Term until 30/09/2027

Salary: AMNL £46,675 to £80,081 (for those below ST3 on 3 August 2016); CADT £65,048 to £73,992 (for those at or above ST3 on 3 August 2016),

The Faculty of Medicine wishes to appoint an NIHR Academic Clinical Lecturer, hosted by one of the following clinical specialties: Clinical Genetics, Obstetrics and Gynaecology or General Surgery.

The post is intended for an applicant within any of these three specialities, with the speciality of the final (single) post dependent on the successful applicant.

The post-holder will be pursuing their development of research and teaching within either the Human Development and Health school or Cancer Sciences school of the Faculty of Medicine, University of Southampton. 

In this post-doctoral role, the successful candidate will be in specialist clinical training at ST3 level or above and have substantial experience of the relevant research areas, a proven track record of high-quality original research publications, the ability to work well in a multidisciplinary, multi-professional team and hold a corresponding NTN.

You will join the NIHR Clinical Integrated Academic Training Programme at the University of Southampton, as an NIHR Academic Clinical Lecturer. The post-holder will also have clinical commitments at University Hospital Southampton NHS Foundation Trust that will lead to the acquisition of clinical skills required for full registration within the specialty.

The post is subject to terms and conditions of service determined by the University of Southampton and in its honorary clinical capacity by the University Hospital Southampton Foundation Trust Board.

Informal enquiries are welcome and should be addressed to: 

Clinical Genetics: Professor Diana Baralle, Professor of Genomic Medicine - email: d.baralle@soton.ac.uk 

Obstetrics and Gynaecology: Professor Ying Cheong, Professor of Reproductive Medicine - email: y.cheong@soton.ac.uk

General Surgery: Professor Ramsey Cutress, Professor of Breast Surgery - email: r.i.cutress@soton.ac.uk

A satisfactory Criminal Records Bureau disclosure at Enhanced level is required for this post.  

The Faculty of Medicine holds an Athena SWAN Silver Award demonstrating commitment to equal opportunities and gender balance in the workplace. The Faculty recognises that applicants may seek flexible working patterns which will be considered as part of the recruitment process. For further information including key benefits designed to help maintain and support employees' well-being and work-life balance, please see our working with us website pages.

Closing Date: 08 May 2026

Section: Clinical

Salary: £38,831 to £73,992 per annum
Full Time Fixed Term (4 years full-time, up to 6 years part-time)

The Southampton Clinical Trials Unit (SCTU) is a UK Cancer Research Collaboration (UKCRC) registered unit and was set up in 2006 to design and conduct academically led clinical trials. The Unit employs trial managers, data managers, statisticians, regulatory staff and administrative support staff. We manage a growing portfolio of multi-centre clinical trials that will directly influence routine clinical practice. The Unit is core funded by Cancer Research UK, has support funding from the NHS National Institute for Health Research, and is based at Southampton University Hospitals NHS Trust.

The Role

We have an exciting opportunity to work within the CTU. You will work with other colleagues in a team supporting our trial management team and will take responsibility for providing high quality administrative support across a range of activities.

About You

You will be a team player with a keen eye for detail and a flexible, can-do attitude. You will have excellent IT and inter-personal skills with a commitment to providing excellent customer service. Previous work experience within an administrative or secretarial support role within a research environment is required.

Terms of Appointment

The employing organisation is the University of Southampton which offers a competitive salary, pension scheme and other benefits. The post is offered on a 12 month fixed term contract. This is a full-time post, but part time may be considered.

The CTU is part of a strong research environment in Southampton which includes the Cancer Research UK Clinical Centre, Experimental Cancer Medicine Centre, Welcome Trust Clinical Research Facility and strong NHS R&D Management.

For an informal discussion about this post please contact Nicole Keyworth, Portfolio Lead on n.e.keyworth@soton.ac.uk.

The Faculty of Medicine holds an Athena SWAN Silver Award demonstrating commitment to equal opportunities and gender balance in the workplace. The Faculty recognises that applicants may seek flexible working patterns which will be considered as part of the recruitment process. For further information including key benefits designed to help maintain and support employees' well-being and work-life balance, please see our working with us website pages.

Closing Date: 22 Apr 2026

Section: Management, Specialist & Administrative

Salary: £27,319 to £30,378 Per annum
Full Time Fixed Term for 12 months

An exciting opportunity is available to join the laboratories of Dr Ali Roghanian and Dr Salah Mansour at the University of Southampton in collaboration with MiNK Therapeutics. We are seeking a collaborative and motivated scientist to work on our new funded programme developing next-generation, off-the-shelf immunotherapies for childhood cancers.

The project will harness engineered cytotoxic invariant Natural Killer T (iNKT) cells for precision targeting of paediatric cancer neoantigens. Building on strong preliminary data, it combines mechanistic and translational immunology with bespoke in vivo models to define and exploit therapeutic candidates. The Research Assistant will lead studies on cytotoxic T cell mechanisms, oversee preclinical validation, and advance TCR-engineered iNKT platforms optimised for immunotherapy.

The role bridges basic and translational research and suits a creative scientist with interests in tumour immunology, T cell engineering, and immunotherapy. You will join a multidisciplinary team spanning immunology, with access to advanced flow cytometry and in vivo platforms.

The funding is initially available for 12 months, with the possibility of extension to 21 months, subject to satisfactory progress.

Key responsibilities

• To work within the Mansour and Roghanian labs, and with collaborators at Southampton, LifeArc and MiNK Therapeutics.
• To design, conduct, and analyse in vitro and in vivo immunology experiments.
• To lead the optimisation and functional assessment of human T cells.
• To liaise and coordinate between project collaborators, including the industrial partner, and core facilities.
• To record analyses accurately and present results at group and collaborative meetings, and conferences.
• To contribute to dissemination of findings through publications and grant applications.
• Any other duties appropriate to the scope and grade of the post.

Essential qualifications, experience and competencies

• Degree (BSc or equivalent) in biological or biomedical sciences or equivalent experience
• Strong practical experience with core immunological assays (e.g., FACS, ELISA, T cell assays).
• Proven competence in the design and execution of experiments using mouse models of cancer.
• Ability to manage projects to timelines, supervise junior staff, and work both independently and collaboratively.
• Excellent communication and presentation skills, including at conferences.

Desirable

• Experience in engineering human T cells, viral transduction, or related approaches.
• Home Office Personal Licence.

About us

The University of Southampton offers a strong environment for translational immunology. Clinical and Experimental Sciences (CES) is a hub for infection and immunology, while the Centre for Cancer Immunology (CCI) is the UK’s first dedicated cancer immunology centre. Together, they unite expertise in T cell biology, multiomics, immunotherapy, preclinical modelling, and clinical translation, supported by an embedded Clinical Trials Unit and close links with NHS and industry partners.

How to apply

Applications must be submitted via the University of Southampton recruitment system by 24th April 2026. Interviews will be held soon after.

Applicants should provide:

• A CV
• A cover letter outlining suitability for the role

Closing Date: 24 Apr 2026

Section: Technical & Experimental

Salary: £36,636 to £37,694 per annum
Full Time Fixed Term for 12 months