You should have extensive laboratory expertise in cell biology and human tissue culture. The role includes extensive work with human pluripotent stem cells and so previous experience and expertise with CRISPR/Cas9 technologies in addition to laboratory leadership would be an advantage. For example some work will include reprogramming hiPSC derived from patient fibroblasts and retinal organoid cultures. You should be a highly motivated candidate, capable of independently designing and carrying out experiments as well as intellectually contributing to the projects and managing multiple workstreams to achieve their goals in a timely manner. You should be interested in the interface between lab-based research and clinical research and ideally have a track record of publishing in high-quality, peer-reviewed journals.

The vision group investigates various aspects of paediatric and adult eye disease from very clinical projects to lab based and genetic studies in-house with multiple collaborations between PI’s in the vision research group. This role is to support those aspects of projects related to stem cell work. Importantly, this includes regular but minimal weekend maintenance work and covering other staff duties where necessary. Hence, this exciting role offers the opportunity to work at the interphase of cutting-edge, multidisciplinary research on multiple ophthalmic disorders. You will join a vibrant and dynamic research group and be expected to work as a team with other postdocs, PhD/undergraduate students, clinician scientists and technicians as part of the wider vision research group. You will collaborate with colleagues across Faculties of Medicine and Biological Sciences at the University of Southampton and colleagues in other institutions. The candidate can expect a collegial and research-focused environment with mentoring and career development support from the line manager Jorn Lakowski and the other vision groups PI team. 

The post is available for a period of 2 years in the first instance. Interviews for shortlisted candidates are likely to be held in March/April 2026. Informal inquires may be directed to Dr. Jorn Lakowski (J.Lakowski@soton.ac.uk). 

Closing Date: 28 Apr 2026

Section: Technical & Experimental

Salary: £31,236 to £35,608
Full Time Fixed Term (2 Years)

We hope to move a compound forward toward Investigational New Drug (IND)-enabling studies and clinical development for severe asthma.

Dr Haitchi’s group studies asthma and in particular the role of the asthma gene ADAM33 in development of asthma using in vivo and in vitro asthma research models.

The posts will be full-time for up to 10 months, funded by a MRC-DPFS grant. 

Candidates must hold or nearing completion of a relevant MSc or PhD qualification (or equivalent). A background in respiratory research with experience in, molecular biology techniques is essential, microscopy and image analysis and animal models is desirable. We especially welcome applications from enthusiastic candidates with prior knowledge of a broad variety of laboratory research methods and human and/or mouse in vivo and ex vivo respiratory disease research models with a keen interest and willingness to learn new research methods as part of a research team in the UK and USA.

We offer an exciting and stimulating work environment. The respiratory research group in CES and the Southampton NIHR-Biomedical Research Centre (BRC) conducts world-class research spanning basic sciences and clinical research for asthma and other lung diseases. The position will be based in the Roger Brooke laboratory.

Besides a great research environment, Southampton and its surrounding provide a beautiful place to live.

More information on the group and BRC:  https://www.southampton.ac.uk/medicine/about/staff/hmha.pageand https://www.uhs.nhs.uk/ClinicalResearchinSouthampton/Research/Facilities/NIHR-Southampton-Biomedical-Research-Centre/NIHRSouthamptonBiomedicalResearchCentre.aspx

Informal enquiries are strongly encouraged and can be made to Dr Hans Michael Haitchi (hmha@soton.ac.uk) - Potential interview dates: April 2026.

The University is committed to equality for all: https://www.southampton.ac.uk/diversity/policies/equal_opportunities.page

Applications for Research Technician positions will be considered from candidates who are working towards or nearing completion of a relevant MSc or PhD qualification.  

Closing Date: 15 Apr 2026

Section: Technical & Experimental

Salary: £31,236 to £39,906
Full Time Fixed Term (until 28/02/2027)

Do you want to play a major role in inspiring the next generation of students in a world-class University? 

This is an exciting opportunity to join the School of Electronics and Computer Science (ECS) as a Biomedical Engineering Teaching Laboratory Supervisor (Maternity cover) to run the new Biomedical Engineering Teaching Labs.

As a Biomedical Engineering Teaching Laboratory Supervisor (Maternity cover) you will be responsible to plan, sustain, and organise the Technical delivery of core undergraduate and taught undergraduate specialist Biomedical Engineering associated with all ECS taught degrees, and, to support the School’s strategic growth of teaching facilities. In this role you will manage the day-to-day running of ECS’s state of the art Biomedical Engineering Teaching Laboratory services and equipment, and to provide specialist Technical support and advice to the School’s practical educational activities.

You must hold a relevant degree qualification and proven chemical experience and practical laboratory skills, and laboratory management. You must have substantial experience in a relevant technical field, with proven experience of successfully planning work activities.

Successful delivery in this role will significantly contribute to protecting the capital investment in ECS teaching facilities and to deliver the maximum educational value from them.

Ranked in the top 1% of universities worldwide, we’re progressive and we push the boundaries of what we’re teaching our students – and what we’re learning alongside them. We encourage and support our staff to pursue their research and develop enterprise activities. With major sector centres including Responsible AI UK, centres for Healthcare Technologies, Flexible Electronics and e-Textiles, and Internet of Things, and modern laboratory facilities from the Zepler cleanrooms to the Tony Davis High Voltage lab, our reputation for teaching, research and enterprise is exceptional. 

Athena SWAN Silver Award recognised, we’re committed to improving equality for women in science and engineering, so we’ll help you find a good work-life balance with flexible or even part-time working hours, with a workload adjusted accordingly. ECS provides a unique, friendly and supportive environment. We have a range of staff development programmes and a unique mentoring and wellbeing scheme. Please visit https://www.ecs.soton.ac.uk/workinghere to find out more about working with us.

The University of Southampton is committed to sustainability and being a globally responsible university and has been awarded the Platinum EcoAward.

For more details contact Katie Chamberlain K.E.Chamberlain@soton.ac.uk or Mr David Oakley do@ecs.soton.ac.uk

Closing Date: 15 Apr 2026

Section: Technical & Experimental

Salary: £36,636 to £44,746 per annum
Full Time Fixed Term for 6 months

An exciting opportunity is available to join the laboratories of Dr Ali Roghanian and Dr Salah Mansour at the University of Southampton in collaboration with MiNK Therapeutics. We are seeking a collaborative and motivated scientist to work on our new funded programme developing next-generation, off-the-shelf immunotherapies for childhood cancers.

The project will harness engineered cytotoxic invariant Natural Killer T (iNKT) cells for precision targeting of paediatric cancer neoantigens. Building on strong preliminary data, it combines mechanistic and translational immunology with bespoke in vivo models to define and exploit therapeutic candidates. The Research Assistant will lead studies on cytotoxic T cell mechanisms, oversee preclinical validation, and advance TCR-engineered iNKT platforms optimised for immunotherapy.

The role bridges basic and translational research and suits a creative scientist with interests in tumour immunology, T cell engineering, and immunotherapy. You will join a multidisciplinary team spanning immunology, with access to advanced flow cytometry and in vivo platforms.

The funding is initially available for 12 months, with the possibility of extension to 21 months, subject to satisfactory progress.

Key responsibilities

• To work within the Mansour and Roghanian labs, and with collaborators at Southampton, LifeArc and MiNK Therapeutics.
• To design, conduct, and analyse in vitro and in vivo immunology experiments.
• To lead the optimisation and functional assessment of human T cells.
• To liaise and coordinate between project collaborators, including the industrial partner, and core facilities.
• To record analyses accurately and present results at group and collaborative meetings, and conferences.
• To contribute to dissemination of findings through publications and grant applications.
• Any other duties appropriate to the scope and grade of the post.

Essential qualifications, experience and competencies

• Degree (BSc or equivalent) in biological or biomedical sciences or equivalent experience
• Strong practical experience with core immunological assays (e.g., FACS, ELISA, T cell assays).
• Proven competence in the design and execution of experiments using mouse models of cancer.
• Ability to manage projects to timelines, supervise junior staff, and work both independently and collaboratively.
• Excellent communication and presentation skills, including at conferences.

Desirable

• Experience in engineering human T cells, viral transduction, or related approaches.
• Home Office Personal Licence.

About us

The University of Southampton offers a strong environment for translational immunology. Clinical and Experimental Sciences (CES) is a hub for infection and immunology, while the Centre for Cancer Immunology (CCI) is the UK’s first dedicated cancer immunology centre. Together, they unite expertise in T cell biology, multiomics, immunotherapy, preclinical modelling, and clinical translation, supported by an embedded Clinical Trials Unit and close links with NHS and industry partners.

How to apply

Applications must be submitted via the University of Southampton recruitment system by 24th April 2026. Interviews will be held soon after.

Applicants should provide:

• A CV
• A cover letter outlining suitability for the role

Closing Date: 24 Apr 2026

Section: Technical & Experimental

Salary: £36,636 to £37,694 per annum
Full Time Fixed Term for 12 months

An exciting opportunity is available to join the laboratories of Dr Ali Roghanian and Dr Salah Mansour at the University of Southampton in collaboration with MiNK Therapeutics. We are seeking a collaborative and motivated scientist to work on our newly funded programme developing next-generation, off-the-shelf immunotherapies for childhood cancers.

This 12 month project will harness engineered cytotoxic invariant Natural Killer T (iNKT) cells for precision targeting of paediatric cancer neoantigens. Building on strong preliminary data, it combines mechanistic and translational immunology with bespoke preclinical models to define and exploit therapeutic candidates. The Research Technician will lead studies on cytotoxic T cell mechanisms, oversee preclinical validation, and advance TCR-engineered iNKT platforms optimised for immunotherapy.

The role bridges basic and translational research and suits a creative scientist with interests in tumour immunology, T cell engineering, and immunotherapy. You will join a multidisciplinary team spanning immunology, with access to advanced flow cytometry and in vivo platforms.

The funding is initially available for 12 months, with the possibility of extension to 21 months, subject to satisfactory progress.

Key responsibilities

• To work within the Mansour and Roghanian labs, and with collaborators at Southampton, LifeArc and MiNK Therapeutics.
• To design, conduct, and analyse in vitro immunology experiments.
• To lead the optimisation and functional assessment of engineered human T cells.
• To liaise and coordinate between project collaborators, including the industrial partner, and core facilities.
• To record analyses accurately and present results at group and collaborative meetings, and conferences.
• To contribute to dissemination of findings through publications and grant applications.
• Any other duties appropriate to the scope and grade of the post.

Essential qualifications, experience and competencies

• Degree (BSc or equivalent) in biological or biomedical sciences or equivalent experience
• Strong practical experience with core immunological assays (e.g., FACS, ELISA, T cell assays).
• Ability to manage projects to timelines, and work both independently and collaboratively.
• Excellent communication and presentation skills, including at conferences.

Desirable

• Experience in engineering human T cells, viral transduction, or related approaches.

About us

The University of Southampton offers a strong environment for translational immunology. Clinical and Experimental Sciences (CES) is a hub for infection and immunology, while the Centre for Cancer Immunology (CCI) is the UK’s first dedicated cancer immunology centre. Together, they unite expertise in T cell biology, multiomics, immunotherapy, preclinical modelling, and clinical translation, supported by an embedded Clinical Trials Unit and close links with NHS and industry partners.

Application

Applicants should provide:

• A CV
• A cover letter outlining suitability for the role
• Contact details for at least two recent referees

Start date: May 2026 or soon after (negotiable)

Closing Date: 26 Apr 2026

Section: Technical & Experimental

Salary: £36,636 to £37,694 per annum
Full Time Fixed Term for 12 months