The post is intended for an applicant within any of these three specialities, with the speciality of the final (single) post dependent on the successful applicant.

The post-holder will be pursuing their development of research and teaching within either the Human Development and Health school or Clinical and Experimental Sciences school of the Faculty of Medicine, University of Southampton.

In this post-doctoral role, the successful candidate will be in specialist clinical training at ST3 level or above and have substantial experience of the relevant research areas, a proven track record of high-quality original research publications, the ability to work well in a multidisciplinary, multi-professional team and hold a corresponding NTN. The applicant will have a higher research degree (or have submitted for such a degree at the time of application) and appropriate research experience.

You will join the NIHR Clinical Integrated Academic Training Programme at the University of Southampton, as an NIHR Academic Clinical Lecturer. The post-holder will also have clinical commitments at University Hospital Southampton NHS Foundation Trust that will lead to the acquisition of clinical skills required for full registration within the specialty.

The post is subject to terms and conditions of service determined by the University of Southampton and in its honorary clinical capacity by the University Hospital Southampton Foundation Trust Board.

Informal enquiries are welcome and should be addressed to:

Palliative Medicine: Dr Stephen Lim, Principal Clinical Research Fellow - email: S.E.Lim@soton.ac.uk

Anaesthetics: Professor Mike Grocott, Professor of Anaesthesia & Critical Care - email: mike.grocott@soton.ac.uk

Respiratory: Professor Mark Jones, Professor of Respiratory - email: mark.jones@soton.ac.uk

A satisfactory DBS check at Enhanced level is required for this post.

Please note: successful applicants will be appointed to a different salary range (AMNL £46,675 to £80,081) if you were at ST3 on or before 2 August 2016.

Closing Date: 07 Sep 2026

Section: Clinical

Salary: £67,325 to £76,582 Per annum
Full Time Fixed Term for 4 years/Part Time Fixed Term for 6 years

An exciting opportunity is available for a talented quantitative researcher to join a public health team working closely with the Healthy Communities and Prevention Theme of the NIHR Applied Research Collaboration (ARC) Wessex which aims to address the systemic drivers of intergenerational health inequality, enabling positive health experiences for marginalised communities and fostering equitable prevention of ill health. 

The post is available under the supervision of Professor Nisreen Alwan and Dr Nida Ziauddeen in close collaboration with the wider Arc Wessex.

The successful candidate will be employed by the Faculty of Medicine, University of Southampton and will be based at the Centre for Population Health Sciences, School of Primary Care, Population Sciences and Medical Education. 

The Healthy Communities and Prevention Theme of the NIHR ARC Wessex has a flagship programme focusing on Obesity Across the Lifecourse. The role will support interdisciplinary quantitative research and modelling towards achieving the aims of the Theme working with the relevant regional and national stakeholders.

Applicants will have substantial experience of conducting quantitative research using cohort or health records data, statistical modelling, working independently and collaboratively with diverse teams. Applicants’ knowledge and experience will have been gained through a relevant PhD and work experience, and demonstrated through peer reviewed publications.

The post is fixed term until 30/09/2028 and will be offered full time from October 2026. Other FTEs will be considered on a case-by-case basis.

For an informal discussion about the post please contact Professor Nisreen Alwan (n,a,alwan@soton.ac.uk) or Dr Nida Ziauddeen (nida.ziauddeen@soton.ac.uk). 

Working at the University of Southampton:

Check out the staff benefits and why you should join us at The University of Southampton.

Closing Date: 20 Aug 2026

Section: Education, Research & Enterprise

Salary: £36,636 to £44,746 per annum
Full Time Fixed Term until 30/09/2028

MASLD is a complex multisystem metabolic disease involving pathological cross‑talk between the liver, adipose tissue, gut, and immune system. The MIMIC programme aims to develop human, immunocompetent, patient‑derived multi‑organ models, using induced pluripotent stem cells (iPSCs) and organ‑on‑chip technologies, to better understand disease mechanisms and accelerate therapeutic discovery. This PDRA post focuses on the development and characterisation of iPSC‑derived adipose tissue models and their integration into multi‑tissue platforms.

The Role

The successful candidate will play a central role in contributing to the generation of biomimetic, immunocompetent adipose tissue constructs derived from human iPSCs. Working closely with stem cell biologists, immunologists, and bioengineers across the MIMIC consortium, the PDRA will:

• Develop and optimise iPSC‑derived adipocyte differentiation protocols 
• Generate 3D adipose tissue organoids incorporating stromal, endothelial, and immune cell populations
• Perform in‑depth molecular, phenotypic and metabolic characterisation of adipose models
• Investigate inflammatory and metabolic dysfunction relevant to MASLD
• Contribute to multi‑organ integration, i.e. adipose–liver–gut cross‑talk 
• Support benchmarking of in‑vitro findings against clinical and patient‑derived data

This role provides an exceptional opportunity to work at the cutting edge of human disease modelling, immunometabolism, and regenerative medicine within a large, well‑funded collaborative programme.

About you

You will hold a PhD/DPhil or equivalent a relevant discipline along with:

• Strong hands‑on experience of stem cell-derived models
• Demonstrated expertise in adipose tissue biology and adipocyte differentiation
• Experience with 3D cell culture, organoid systems, or co‑culture models
• Solid grounding in molecular and cellular biology techniques 
• Ability to work both independently and collaboratively within a large interdisciplinary programme

Informal enquiries are welcome and may be directed to: Jaswinder Sethi (j.sethi@soton.ac.uk). Please note that applications sent only to this email address will not be accepted.

What we offer 

• An exciting post within a high‑profile UKRI‑funded research programme
• Access to world‑class facilities and international collaborators
• Strong mentorship and career development, including training and conference support
• Opportunities for collaboration, secondments, and interdisciplinary skills development
• A generous holiday allowance as well as additional university closure days
• A vibrant, inclusive, and supportive research environment

Closing Date: 01 Sep 2026

Section: Education, Research & Enterprise

Salary: £36,636 to £41,064 Per Annum
Full Time Fixed Term for 24 months

SCTU is a leading UK academic CTU located within the state-of-the-art Centre for Cancer Immunology building at Southampton General Hospital. Southampton Clinical Trials Unit (SCTU) | University of Southampton

SCTU is a UKCRC registered CTU and is core-funded by Cancer Research UK (CRUK) together with funding from the National Institute for Health and Care Research (NIHR) via the Biomedical Research Centre (BRC) and Research Support Service (RSS). 

SCTU has expertise in the design, conduct and publication of clinical trials and other well-designed studies from first-in-human phase I to practice changing phase III trials to large early diagnosis observational studies with rich translational data. Managing a growing portfolio (75% cancer, 25% non-cancer) that covers the complete spectrum of clinical practice, from primary care through to tertiary referral medicine, including pan-cancer experimental therapeutics, surgery, radiotherapy and early diagnosis. Undertaking multi-centre early and late phase clinical trials, we work nationally and internationally to create the evidence for patient benefit that will directly influence routine clinical practice in the NHS and overseas. 

As part of the CRUK and NIHR infrastructure we have close working relationships with our partners, including the Southampton Experimental Cancer Research Centre, NIHR BRC & RSS, University Hospital Southampton, the Centre for Cancer Immunology discovery community and CRUK Centres and Institutes across the UK, with an increasing number of international collaborations. 

The Senior Trials Manager will lead the relevant portfolio team to ensure effective delivery of the overall strategy and delivery priorities for SCTU. This will include resource management, oversight of financial management, new trial development, grant applications, and the ability to anticipate and consider potential issues or opportunities which could affect delivery and growth of the relevant portfolio.

The appointed person must have proven experience of running clinical trials, with a focus on multistakeholder studies collecting patient samples for analysis, and including new trial development.

This position is full time, or part time (minimum 0.6FTE), fixed term for 24 months. 

The employing organisation is the University of Southampton which offers a competitive salary, pension scheme, generous holiday entitlement and other benefits. 

For informal queries please contact Nicole Keyworth, Portfolio Lead, on n.e.keyworth@soton.ac.uk

Closing Date: 31 Aug 2026

Section: Management, Specialist & Administrative

Salary: £46,049 to £58,225 per annum
Full Time Fixed Term for 24 months