Working as part of a dynamic translational research team consisting of basic and clinical scientists within the NIHR Southampton Biomedical Research Centre, the successful candidate will be based in the Brooke Laboratory at University Hospital Southampton. 

The role will involve human lung tissue and bronchoalveolar lavage analyses, 3D cell culture (including primary cells), analysis of cell responses by molecular and cellular techniques including ELISA, RT-qPCR, and manipulation of cells by pharmacological and gene knock-out/knock-in techniques. 

For this position, you must have a PhD or equivalent professional qualifications and experience in cell and molecular biology. Experience of cell culture and at least some of the techniques listed above is essential, while experience in primary lung cell culture, 3D culture techniques, and (immuno)histochemistry is desirable.

The ideal candidate will be able to adapt to working with a variety of techniques across different laboratories, working efficiently and diligently, with a strong work ethic and able to use their own initiative.  They will be team-oriented, with excellent organisational skills, and reliable.  The successful applicant must have excellent spoken and written English communication skills.

This is a full time fixed term role until 31^st March 2027.

For informal enquiries, please contact Professor Mark Jones - mark.jones@soton.ac.uk

Applications for Research Fellow positions will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification.

Closing Date: 22 Oct 2026

Section: Education, Research & Enterprise

Salary: £37,369 Per annum
Full Time Fixed Term until 31/03/2027

Due to new grant awards, we have a vacancy for a Trial Manager to join our established Non-Cancer Trials team to develop and manage one or more studies within a diverse and expanding portfolio. This is an exciting opportunity for someone with previous clinical trials experience to join a CTU which has full registration status from the UK Clinical Research Collaboration (UKCRC).

The successful applicant will have experience of working in clinical trials within the NHS, academic or commercial health research sector. They will contribute to the delivery of complex intervention studies conducted across a range of healthcare settings, including community, primary care, hospice and home-based environments. The portfolio includes research involving adults with significant health and care needs, including potentially vulnerable populations, where trial delivery must be integrated into routine clinical care pathways.

The role requires excellent organisational and communication skills and the ability to work effectively within complex stakeholder environments, collaborating with clinicians, community healthcare teams, hospices, primary care providers, research networks, patient representatives and external partners. Experience of coordinating multi-centre studies, managing competing priorities, supporting site set-up and oversight, and navigating operational challenges associated with pragmatic trial delivery would be advantageous.

The successful applicant will have a good understanding of Good Clinical Practice (GCP), clinical trial regulations and risk-based approaches to trial management. They will support studies addressing important healthcare challenges, including the evaluation of interventions delivered in community and home-based settings and research conducted within palliative and end-of-life care pathways. A flexible and participant-centred approach will be essential, together with a commitment to maintaining the highest standards of participant safety, data quality and trial governance.

The employing organisation is the University of Southampton, which offers a competitive salary, pension scheme and a wide range of staff benefits. The post is offered on a one-year fixed-term contract in the first instance, with the possibility of extension.

The CTU is part of a strong research environment in Southampton which includes the Cancer Research UK Clinical Centre, Experimental Cancer Medicine Centre, Wellcome Trust Clinical Research Facility and strong NHS R&D Management.

Location: Hybrid – There is a requirement to work in the office at Southampton at least 60% of contracted hours

For an informal discussion about this post please contact Jacqui Nuttall J.Nuttall@soton.ac.uk 

Closing Date: 27 Oct 2026

Section: Management, Specialist & Administrative

Salary: £37,369 to £45,641 Per Annum
Full Time Fixed Term for 12 months

Full Time - Fixed Term for 24 months (part time may be considered at 0.8 fte)

The Southampton Clinical Trials Unit (CTU), based at Southampton General Hospital, manages a growing portfolio of multi-centre clinical trials that will directly influence routine clinical practice. 

Due to new grant awards we have a vacancy for a Trial Manager to join the existing team to develop and manage one or more trials. This is an exciting opportunity for someone with previous clinical trials experience to join a CTU which has full registration status from the UK Clinical Research Collaboration (UKCRC). 

The successful applicant will have significant experience of clinical trials in the NHS or the commercial health research sector. They will also have excellent organisation and communication skills, a good understanding and knowledge of GCP and clinical trial regulations.

The employing organisation is the University of Southampton which offers a competitive salary, pension scheme and other benefits. The post is offered on a two year fixed term contract in the first instance with the possibility of an extension. This is advertised as a full time position, though part time may be considered (minimum 0.8 FTE).

The CTU is part of a strong research environment in Southampton which includes the Cancer Research UK Clinical Centre, Experimental Cancer Medicine Centre, Wellcome Trust Clinical Research Facility and strong NHS R&D Management.

For an informal discussion about this post please contact Denise Dunkley d.dunkley@soton.ac.uk or Kelly Cozens kc8@southampton.ac.uk 

The Faculty of Medicine holds an Athena SWAN Silver Award demonstrating commitment to equal opportunities and gender balance in the workplace. The Faculty recognises that applicants may seek flexible working patterns which will be considered as part of the recruitment process. For further information including key benefits designed to help maintain and support employees' well-being and work-life balance, please see our working with us website pages.

Working at the University of Southampton:

Check out the staff benefits and why you should join us at The University of Southampton.

Closing Date: 23 Oct 2026

Section: Management, Specialist & Administrative

Salary: £36,636 to £44,746 per annum
Full Time Fixed Term for 24 months