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Mechanistic understanding of the relationships between oxidative and electrophilic stress in allergic skin sensitisation.

School of Biological Sciences

Location:  Highfield Campus
Closing Date:  Monday 31 August 2020
Reference:  1280720BJ

PhD Supervisor: Dr Paul Skipp                                  co supervisor: TBD

Interviews will be held in September 2020 (interview format to be advised due to COVID-19)

PhD Description: Oxidative and electrophilic stress are series of complex cellular responses to normal physiological and pathophysiological processes. Cellular adaptations have allowed for exposure to a variety of reactive molecules or intermediates by evolution of defence mechanisms which scavenge these intermediates and repair the damage caused. There is a current interest in the mechanistic understanding of oxidative and electrophilic stress, particularly resulting from exposure to chemicals which induce a variety of stress responses. This project will employ a range of cell biology, proteomic and bioinformatic approaches to bring new understanding of the crucial roles oxidative and electrophilic stress play in allergic skin sensitisation.

The project is funded for 4 years and welcomes applicants from the UK who have or expect to obtain at least an upper second class degree in Biological Sciences or allied subjects. Funding will cover fees and a stipend at current research council rates of £15,285 per annum for 2020/21. 

Due to funding restrictions this position is only open to UK applicants

Applications for a PhD in Biological Sciences should be submitted online at:

https://studentrecords.soton.ac.uk/BNNRPROD/bzsksrch.P_Login?pos=4973&majr=4973&term=202021  Please place Dr Paul Skipp’s name in the field for proposed supervisor.

General enquiries should be made to Dr Paul Skipp (pjss@soton.ac.uk).

Any queries on the application process should be made to fels-pgr-apply@soton.ac.uk

Applications will be considered in the order that they are received, and the position will be considered filled when a suitable candidate has been identified

The University of Southampton and the School of Biological Sciences both hold an Athena Swan Silver Award, demonstrating their commitment to provide equal opportunities and to advance the representation of women in STEM/M subjects: science, technology, engineering, mathematics and medicine.   Due consideration will be given to applicants who have taken a career break.  University benefits include onsite childcare facilities, state-of-the-art on-campus sports, arts and culture facilities, a full programme of events and a range of staff discounts.

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