Due to expansion, we currently have a vacancy for a Senior Trial Manager to join the existing cancer portfolio team. The Senior Trial Manager will be responsible for the oversight of trials ensuring they are delivered according to required standards, time and budget. This is a senior post within the CTU with advisory, leadership, engagement, and line management responsibilities.

The appointed Senior Trial Manager will work specifically on a single trial developing SCTU expertise into clinical collaboration opportunities with industry partners, where an academically sponsored trial will result is supporting MHRA drug licencing, which aims to fulfil faster movement from research to patient access.

The successful candidate will have significant experience of trial management gained through working on interventional clinical trials, including experience of IMP management, and have excellent knowledge of legislation, regulation and governance environments relating to clinical trials. The Senior Trial Manager will be required to work with multiple stakeholders so must have an excellent communication style and experience of matrix management, as well as the ability to multi-task, meet deadlines and be a good leader and line manager. Experience of regulatory affairs including submitting drugs for licencing would be an advantage.

SCTU is a leading UK academic CTU located within the state-of-the-art Centre for Cancer Immunology building within the University of Southampton, based at Southampton General Hospital. Having patient benefit at the heart of everything it does, SCTU is a UKCRC registered CTU and is core-funded by Cancer Research UK (CRUK) together with funding from the National Institute for Health and Care Research (NIHR) via the Biomedical Research Centre (BRC) and Research Support Service (RSS). Southampton Clinical Trials Unit (SCTU) | University of Southampton

The CTU is part of a strong research environment in Southampton which includes the Experimental Cancer Medicine Centre, Clinical Research Facility and strong links with The University Hospital Southampton NHS Foundation Trust NHS R&D Management.

The employing organisation is the University of Southampton which offers a competitive salary, pension scheme and other benefits. The post is offered on a two year full-time fixed term contract in the first instance with the possibility of an extension; part time may be considered at 0.8 FTE. This will be a hybrid role with a requirement to work in the office in Southampton at least 60% of contracted hours. Working at the University of Southampton provides many benefits: Check out the staff benefits page.

For an informal discussion please contact Andrea Corkhill, Head of Trial Management, Oncology akc@soton.ac.uk

Please note, this advert may close early, so early applications are advised.

Closing Date: 17 Aug 2026

Section: Management, Specialist & Administrative

Salary: £46,049 to £58,225 per annum
Full Time Fixed Term for 2 years

The University of Southampton Clinical Trials Unit (SCTU) is a Cancer Research UK core-funded, UKCRC registered trials unit. The unit supports researchers across the UK and internationally to help design, conduct, analyse and disseminate clinical trials and observational studies that target important clinical and social health care questions.

The role

The unit is seeking to employ a senior medical statistician with experience of working on clinical trials in a regulated environment. The post is covering maternity leave, and will have responsibilities for delivering the urological cancer portfolio, which includes two large phase 3 trials in bladder and prostate cancer. You will work with junior statisticians and statistical programmers to oversee delivery of trial reports. You will plan work and communicate with the Head of Group in Statistics to support management of workload across the team. You will lead communication with chief investigators and the wider trial team on methodological issues, and more broadly support the SCTU to deliver the assigned trials.

The role requires knowledge of the application of statistical methods to cancer trials, as well as activities relating to obtaining funding and dissemination of study results. Familiarity with statistical software such as Stata, SAS and/or R is essential. An applicant should be able to demonstrate an ability to work to timelines across multiple complex projects, and have experience of working in multidisciplinary teams.

Full-time or part-time (0.6FTE or above). This is a fixed term post until 02/07/2027 to cover maternity leave.

What we can offer you

Working at the University of Southampton gives you access to a wide range of benefits in addition to our competitive rates of pay. Our core benefits include pension scheme membership; a generous annual leave allowance (supplemented by University closure days and public holidays) and excellent family leave arrangements (including maternity, paternity, adoption and parental leave).

https://www.southampton.ac.uk/hr/services/benefits-explained/index.page

As a university we aim to create an environment where everyone can thrive and are proactive in fostering a culture of inclusion, respect and equality of opportunity. We believe that we can only truly meet our objectives if we are reflective of society, so we are passionate about creating a working environment in which you are free to bring your whole self to work. We welcome candidates form any and all backgrounds, who are committed to helping us create an inclusive work environment. We encourage applications from candidates from Black, Asian and Minority Ethnic communities, from the Global South, from people who identify as LGBTQ+, from people with disabilities, and from first generation higher education attendees.

Committed to supporting our teaching and research community we are open to flexible working. With an understanding that there is a need to be on site in order to completely fulfil the role, we are open to a hybrid approach. We give full consideration to applicants that wish to work flexibly including part-time and those who have taken a career break. We are proud to be a founding signatory of the Athena Swan gender equality charter, and hold an institutional Silver award.

Working at the University of Southampton:

Check out the staff benefits and why you should join us at The University of Southampton.

Closing Date: 13 Jul 2026

Section: Education, Research & Enterprise

Salary: £46,049 to £58,225 per annum
Full Time Fixed Term until 02/07/2027

The position is associated with the laboratory of Professors Ward and Ober. Their interdisciplinary research program is dedicated to the development of novel antibody-based therapeutics for the treatment of cancer and autoimmunity. This research has led to several therapeutics that are currently in advanced clinical trials or approved for clinical use. The group also develops advanced microscopy techniques for the evaluation of novel therapeutics in cellular environments. Their research is supported by major grants from the Welcome Trust, Cancer Research UK and support from collaborating biopharma companies.

The appointee will be highly motivated and excited by the challenges involved in supporting a dynamic, interdisciplinary group of researchers. The appointee’s role will be to provide support with the day-to-day running of the laboratory by providing technical support for the experimental work of post-doctoral fellows, research scientists and graduate students, combined with the ordering and maintenance of laboratory instrumentation and supplies. The position holder will be expected to be familiar with biosafety and other regulatory processes and follow these procedures as necessary.

It is essential to have a skill level equivalent to achievement of HNC, A-Level, NVQ3 with proven work experience acquired in relevant technical support roles and job-related training. The role requires the ability to plan and organise your workload, work well under pressure and communicate effectively and professionally with other laboratory members. A scientific knowledge in a biological field equivalent to B.Sc. level is extremely desirable.

The post-holder will possess relevant academic qualifications and work experience as well as good IT skills.

The position is for one year. Availability of funds for a period beyond the one-year timeframe is anticipated.

Informal enquiries should be directed to Professor Sally Ward (e.s.ward@soton.ac.uk).

Closing Date: 03 Aug 2026

Section: Technical & Experimental

Salary: £31,236 to £35,608 per annum
Full Time Fixed Term for 12 months

The position is associated with the laboratory of Professors Ward and Ober. Their interdisciplinary research program is dedicated to the development of novel antibody-based therapeutics for the treatment of cancer and autoimmunity. This research has led to several therapeutics that are currently in advanced clinical trials or approved for clinical use. The group also develops advanced microscopy techniques for the evaluation of novel therapeutics in cellular environments. Their research is supported by major grants from the Welcome Trust, Cancer Research UK and support from collaborating biopharma companies.

The appointee will be highly motivated and excited by the challenges involved in supporting a dynamic, interdisciplinary group of researchers. The appointee’s role will be to provide support with the day-to-day running of the laboratory by providing technical support for the experimental work of post-doctoral fellows, research scientists and graduate students, combined with the ordering and maintenance of laboratory instrumentation and supplies. The position holder will be expected to be familiar with biosafety and other regulatory processes and follow these procedures as necessary.

It is essential to have a skill level equivalent to achievement of HNC, A-Level, NVQ3 with proven work experience acquired in relevant technical support roles and job-related training. The role requires the ability to plan and organise your workload, work well under pressure and communicate effectively and professionally with other laboratory members. A scientific knowledge in a biological field equivalent to B.Sc. level is extremely desirable.

The post-holder will possess relevant academic qualifications and work experience as well as good IT skills.

The position is for one year. Availability of funds for a period beyond the one-year timeframe is anticipated.

Informal enquiries should be directed to Professor Sally Ward (e.s.ward@soton.ac.uk).

Closing Date: 14 Jul 2026

Section: Technical & Experimental

Salary: £31,236 to £35,608 per annum
Full Time Fixed Term for 12 months