SCTU is a leading UK academic CTU located within the state-of-the-art Centre for Cancer Immunology building at Southampton General Hospital. Southampton Clinical Trials Unit (SCTU) | University of Southampton

SCTU is a UKCRC registered CTU and is core-funded by Cancer Research UK (CRUK) together with funding from the National Institute for Health and Care Research (NIHR) via the Biomedical Research Centre (BRC) and Research Support Service (RSS). 

SCTU has expertise in the design, conduct and publication of clinical trials and other well-designed studies from first-in-human phase I to practice changing phase III trials to large early diagnosis observational studies with rich translational data. Managing a growing portfolio (75% cancer, 25% non-cancer) that covers the complete spectrum of clinical practice, from primary care through to tertiary referral medicine, including pan-cancer experimental therapeutics, surgery, radiotherapy and early diagnosis. Undertaking multi-centre early and late phase clinical trials, we work nationally and internationally to create the evidence for patient benefit that will directly influence routine clinical practice in the NHS and overseas. 

As part of the CRUK and NIHR infrastructure we have close working relationships with our partners, including the Southampton Experimental Cancer Research Centre, NIHR BRC & RSS, University Hospital Southampton, the Centre for Cancer Immunology discovery community and CRUK Centres and Institutes across the UK, with an increasing number of international collaborations. 

The Senior Trials Manager will lead the relevant portfolio team to ensure effective delivery of the overall strategy and delivery priorities for SCTU. This will include resource management, oversight of financial management, new trial development, grant applications, and the ability to anticipate and consider potential issues or opportunities which could affect delivery and growth of the relevant portfolio.

The appointed person must have proven experience of running clinical trials, with a focus on multistakeholder studies collecting patient samples for analysis, and including new trial development.

This position is full time fixed term for 24 months. 

The employing organisation is the University of Southampton which offers a competitive salary, pension scheme, generous holiday entitlement and other benefits. 

For informal queries please contact Nicole Keyworth, Portfolio Lead, on n.e.keyworth@soton.ac.uk

Working at the University of Southampton:

Check out the staff benefits and why you should join us at The University of Southampton.

Closing Date: 02 Jun 2026

Section: Management, Specialist & Administrative

Salary: £46,049 to £58,225 per annum
Full Time Fixed Term for 24 months

Closing Date: 25 May 2026

Section: Education, Research & Enterprise

Salary: £36,636 to £44,746 Per annum
Full Time Fixed Term until 31/01/2029

In this role, you will apply a range of advanced laboratory techniques based around cell culture, maintain high‑quality research facilities, and work closely with other researchers on the programme researchers in a collegiate environment that encourages team working and excellent communication.

Salary is on the Level 3 technical scale.; spine point 22-27 and salary £31,236-£35,608 per annum.

The appointment is from 1st August 2026.

Closing Date: 08 Jun 2026

Section: Technical & Experimental

Salary: £31,236 to £35,608 per annum
Full Time Fixed Term until 31/01/2029

About the position 

An exciting opportunity has arisen at the newly configured Lifecourse Epidemiology Centre (LEC) at the University of Southampton for a Senior Statistical Epidemiologist with an interest in musculoskeletal health research.

The successful applicant will help deliver the analytical strategy and advanced statistical methods for the Arthritis UK Stratification of Osteoarthritis to promote LiVing well and treatment Effectiveness (SOLVE) Research Consortium. The consortium brings together leading UK researchers to identify subtypes, mechanisms and risk factors in osteoarthritis to improve care. The post-holder will work with large epidemiological cohorts (including UK Biobank and the UK Clinical Practice Research Datalink (CPRD)) to quantify risk relationships, elucidate mechanisms, and develop a clinical risk prediction tool for hip or knee replacement.

The LEC at the University of Southampton, reconfigured from forerunning MRC infrastructure, hosts world leading research into the determinants and mechanisms of chronic musculoskeletal diseases of ageing, principally osteoporosis, osteoarthritis and sarcopenia.

The successful applicant must have an MSc in statistics or a closely related discipline, as well as a PhD, and have experience working as a statistical epidemiologist. Previous experience of implementing machine learning methods and developing research funding applications is desirable. This post requires excellent written and oral communication skills, and the ability to work independently and in a multidisciplinary team.

The post-holder will be expected to spend a minimum of 60% of their time physically present at the LEC, located on the Southampton General Hospital site. The post is Full-Time Fixed Term, with appointment for 1-year in first instance (full-time preferred but part-time may be considered), potentially extendable for up to a further 3 years.

Please note your post title upon offer will be Senior Research Fellow.

What we can offer you

Working at the University of Southampton gives you access to a wide range of benefits in addition to our competitive rates of pay. Our core benefits include pension scheme membership; a generous annual leave allowance (supplemented by university closure days and public holidays) and excellent family leave arrangements (including maternity, paternity, adoption and parental leave). Committed to supporting our staff and students, we are open to a flexible working approach. We give full consideration to applicants that wish to work flexibly and those who have taken a career break. As a university we aim to create an environment where everyone can thrive and are proactive in fostering a culture of inclusion, respect and equality of opportunity.

For an informal discussion about the position, please jointly email Prof Nicholas Harvey (nch@mrc.soton.ac.uk) and Dr Leo Westbury (lw@mrc.soton.ac.uk)

Closing Date: 02 Jun 2026

Section: Education, Research & Enterprise

Salary: £46,049 to £51,753 Per Annum
Full Time Fixed Term for 12 months

The post is intended for an applicant within any of these three specialities, with the speciality of the final (single) post dependent on the successful applicant.

The post-holder will be pursuing their development of research and teaching within either the Primary Care, Population Science and Medical Education school, Human Development and Health school or Clinical and Experimental Sciences school of the Faculty of Medicine, University of Southampton.  

In this post-doctoral role, the successful candidate will be in specialist clinical training at ST3 level or above and have substantial experience of the relevant research areas, a proven track record of high-quality original research publications, the ability to work well in a multidisciplinary, multi-professional team and hold a corresponding NTN.

You will join the NIHR Clinical Integrated Academic Training Programme at the University of Southampton, as an NIHR Academic Clinical Lecturer. The post-holder will also have clinical commitments at University Hospital Southampton NHS Foundation Trust that will lead to the acquisition of clinical skills required for full registration within the specialty.

The post is subject to terms and conditions of service determined by the University of Southampton and in its honorary clinical capacity by the University Hospital Southampton Foundation Trust Board.

Informal enquiries are welcome and should be addressed to: 

Public Health: Professor Simon Fraser, Professor of Public Health - email: s.fraser@soton.ac.uk

Paediatrics: Professor Graham Roberts, Professor of Paediatric Allergy & Respiratory Medicine - email: g.c.roberts@soton.ac.uk

Ophthalmology: Professor Andrew Lotery, Professor of Ophthalmology - email: a.j.lotery@soton.ac.uk

A satisfactory Criminal Records Bureau disclosure at Enhanced level is required for this post.

Please note: successful applicants will be appointed to a different salary range (AMNL £46,675 to £80,081) if they were at ST3 on or before 2 August 2016. 

The Faculty of Medicine holds an Athena SWAN Silver Award demonstrating commitment to equal opportunities and gender balance in the workplace. The Faculty recognises that applicants may seek flexible working patterns which will be considered as part of the recruitment process. For further information including key benefits designed to help maintain and support employees' well-being and work-life balance, please see our working with us website pages.

Closing Date: 21 May 2026

Section: Clinical

Salary: £65,048 to £73,992 per annum
Full Time Fixed Term for 4 years (up to 6 years part-time)

The post is intended for an applicant within any of these three specialities, with the speciality of the final (single) post dependent on the successful applicant. 

The post-holder will be pursuing their development of research and teaching within the Faculty of Medicine, University of Southampton. 

In this post-doctoral role, the successful candidate will be in specialist clinical training at ST3 level or above and have substantial experience of the relevant research areas, a proven track record of high-quality original research publications, the ability to work well in a multidisciplinary, multi-professional team and hold a corresponding NTN. 

You will join the NIHR Clinical Integrated Academic Training Programme at the University of Southampton, as an NIHR Academic Clinical Lecturer. The post-holder will also have clinical commitments at University Hospital Southampton NHS Foundation Trust that will lead to the acquisition of clinical skills required for full registration within the specialty.

The post is subject to terms and conditions of service determined by the University of Southampton and in its honorary clinical capacity by the University Hospital Southampton Foundation Trust Board.

Informal enquiries are welcome and should be addressed to: 

Paediatrics, Professor Graham Roberts, Professor of Paediatric Allergy & Respiratory Medicine email: g.c.roberts@soton.ac.uk 

Ophthalmology, Professor Andrew Lotery, Professor of Ophthalmology, email: a.j.lotery@soton.ac.uk

Respiratory Medicine, Professor Mark Jones, Professor of Respiratory Medicine email: mark.jones@soton.ac.uk 

A satisfactory Criminal Records Bureau disclosure at Enhanced level is required for this post. 

Please note: successful applicants will be appointed to a different salary range (AMNL £46,675 to £80,081) for those below ST3 on 3 August 2016; (CADT £65,048 to £73,992) for those at or above ST3 on 3 August 2016.

The Faculty of Medicine holds an Athena SWAN Silver Award demonstrating commitment to equal opportunities and gender balance in the workplace. The Faculty recognises that applicants may seek flexible working patterns which will be considered as part of the recruitment process. For further information including key benefits designed to help maintain and support employees' well-being and work-life balance, please see our working with us website pages.

Closing Date: 22 May 2026

Section: Clinical

Salary: £65,048 to £80,081 per annum
Full Time Fixed Term (4 years full-time, up to 6 years part-time)

The successful candidate will be responsible for designing, implementing, and maintaining Microsoft Azure-based infrastructure, ensuring that the SDE meets stringent security, governance, and compliance requirements associated with clinical research. The role requires experience with cloud platforms, infrastructure as code, and modern DevOps practices, alongside an understanding of networking, monitoring, and system reliability. Experience or interest in the clinical trials or healthcare domain, including the use of informatics and IT to support research, will be highly beneficial.

This position offers the opportunity to contribute to innovative projects in medical research while working in a collaborative and supportive environment. The ideal candidate will demonstrate initiative, creativity, and a genuine interest in applying technology to improve healthcare outcomes, along with strong problem-solving skills and the ability to work both independently and as part of a team.

The University of Southampton offers excellent career development and training opportunities as well as a generous holiday allowance (30 days) including bank holidays (8 days) and paid closure days (6 days). 

The University of Southampton gives you access to a wide range of benefits in addition to our competitive rates of pay and pension scheme membership and excellent family leave arrangements. 

If you would like to discuss the job with a member of the CIRU team please contact Lawrence Surey on ciru@soton.ac.uk

Closing Date: 13 May 2026

Section: Management, Specialist & Administrative

Salary: £36,636 to £44,746 per annum
Full Time Fixed Term until 30/09/2027