The post is intended for an applicant within any of these three specialities, with the speciality of the final (single) post dependent on the successful applicant.

The post-holder will be pursuing their development of research and teaching within either the Human Development and Health school or Clinical and Experimental Sciences school of the Faculty of Medicine, University of Southampton.

In this post-doctoral role, the successful candidate will be in specialist clinical training at ST3 level or above and have substantial experience of the relevant research areas, a proven track record of high-quality original research publications, the ability to work well in a multidisciplinary, multi-professional team and hold a corresponding NTN. The applicant will have a higher research degree (or have submitted for such a degree at the time of application) and appropriate research experience.

You will join the NIHR Clinical Integrated Academic Training Programme at the University of Southampton, as an NIHR Academic Clinical Lecturer. The post-holder will also have clinical commitments at University Hospital Southampton NHS Foundation Trust that will lead to the acquisition of clinical skills required for full registration within the specialty.

The post is subject to terms and conditions of service determined by the University of Southampton and in its honorary clinical capacity by the University Hospital Southampton Foundation Trust Board.

Informal enquiries are welcome and should be addressed to:

Palliative Medicine: Dr Stephen Lim, Principal Clinical Research Fellow - email: S.E.Lim@soton.ac.uk

Anaesthetics: Professor Mike Grocott, Professor of Anaesthesia & Critical Care - email: mike.grocott@soton.ac.uk

Respiratory: Professor Mark Jones, Professor of Respiratory - email: mark.jones@soton.ac.uk

A satisfactory DBS check at Enhanced level is required for this post.

Please note: successful applicants will be appointed to a different salary range (AMNL £46,675 to £80,081) if you were at ST3 on or before 2 August 2016.

Closing Date: 07 Sep 2026

Section: Clinical

Salary: £67,325 to £76,582 Per annum
Full Time Fixed Term for 4 years/Part Time Fixed Term for 6 years

We are seeking an outstanding Research Fellow to join an ambitious translational oncology programme focused on improving precision treatment approaches for patients with gastrointestinal cancers.

This funded programme brings together laboratory scientists, clinicians, and molecular researchers to develop clinically relevant approaches for understanding therapeutic response and resistance in cancer.

The post offers a rare opportunity to contribute to a highly translational initiative operating at the interface of discovery science and patient care. The successful candidate will play a central role in shaping experimental strategy, generating clinically relevant biological insights, and supporting the progression of the programme towards future clinical application.

This is not a conventional postdoctoral role centred on a predefined set of experiments. It is an opportunity to contribute to the development of an evolving translational research platform with clear real-world relevance.

The Role

The Research Fellow will contribute to the scientific and translational development of the programme, including:

• developing and optimising advanced experimental cancer models 
• leading functional studies examining therapeutic response and resistance 
• integrating biological and molecular data to support translational interpretation 
• contributing to clinically relevant reporting and communication of findings 
• supporting regulatory, governance, and translational preparation activities 
• helping shape experimental direction in collaboration with clinical and scientific investigators 

The role requires a high degree of scientific independence, critical thinking, and translational judgement.

What we are looking for

We are seeking an individual with strong experimental expertise and an interest in clinically relevant cancer research.

Essential:

• PhD (or equivalent) in cancer biology or a related discipline 
• Strong background in experimental oncology or cellular/molecular biology 
• Experience developing or optimising complex biological assays or model systems 
• Ability to interpret multifaceted biological data critically 
• Excellent communication and organisational skills 
• Evidence of scientific writing and publication 

Desirable:

• Experience working with translational or clinically aligned research programmes 
• Familiarity with cancer therapeutics, resistance biology, or tumour modelling 
• Experience integrating molecular and functional datasets 
• Understanding of research governance, ethics, or regulatory frameworks 
• Experience working within multidisciplinary environments

The Environment

The successful candidate will join a collaborative multidisciplinary research environment spanning:

• translational cancer biology 
• clinical oncology and surgery 
• molecular profiling and computational analysis 

The programme provides access to established infrastructure, high-quality clinical material, and strong translational support across Southampton and partner clinical centres.

Why this role is different

This position offers the opportunity to work within a genuinely translational programme designed with future clinical application in mind.

You will contribute not only to experimental delivery, but also to the development of approaches capable of bridging laboratory discovery and clinical decision-making.

The role is particularly suited to candidates interested in:

• translational cancer research 
• clinically impactful science 
• multidisciplinary programme development 
• future leadership in translational oncology 

Career Development

The post provides excellent opportunities for career progression and scientific development, including exposure to:

• translational programme leadership 
• multidisciplinary clinical–scientific collaboration 
• clinically aligned research strategy 
• future grant and fellowship development

Informal enquiries

For informal discussion of the role, please contact the Innovation for Translation Research Group leads:

Professor Zoë Walters (Z.S.Walters@soton.ac.uk)
Professor Tim Underwood (T.J.Underwood@soton.ac.uk)

Closing Date: 13 Aug 2026

Section: Education, Research & Enterprise

Salary: £36,636 to £47,389 per annum
Full Time Fixed Term until 31/08/2029

An exciting opportunity is available for a talented quantitative researcher to join a public health team working closely with the Healthy Communities and Prevention Theme of the NIHR Applied Research Collaboration (ARC) Wessex which aims to address the systemic drivers of intergenerational health inequality, enabling positive health experiences for marginalised communities and fostering equitable prevention of ill health. 

The post is available under the supervision of Professor Nisreen Alwan and Dr Nida Ziauddeen in close collaboration with the wider Arc Wessex.

The successful candidate will be employed by the Faculty of Medicine, University of Southampton and will be based at the Centre for Population Health Sciences, School of Primary Care, Population Sciences and Medical Education. 

The Healthy Communities and Prevention Theme of the NIHR ARC Wessex has a flagship programme focusing on Obesity Across the Lifecourse. The role will support interdisciplinary quantitative research and modelling towards achieving the aims of the Theme working with the relevant regional and national stakeholders.

Applicants will have substantial experience of conducting quantitative research using cohort or health records data, statistical modelling, working independently and collaboratively with diverse teams. Applicants’ knowledge and experience will have been gained through a relevant PhD and work experience, and demonstrated through peer reviewed publications.

The post is fixed term until 30/09/2028 and will be offered full time from October 2026. Other FTEs will be considered on a case-by-case basis.

For an informal discussion about the post please contact Professor Nisreen Alwan (n,a,alwan@soton.ac.uk) or Dr Nida Ziauddeen (nida.ziauddeen@soton.ac.uk). 

Working at the University of Southampton:

Check out the staff benefits and why you should join us at The University of Southampton.

Closing Date: 20 Aug 2026

Section: Education, Research & Enterprise

Salary: £36,636 to £44,746 per annum
Full Time Fixed Term until 30/09/2028

MASLD is a complex multisystem metabolic disease involving pathological cross‑talk between the liver, adipose tissue, gut, and immune system. The MIMIC programme aims to develop human, immunocompetent, patient‑derived multi‑organ models, using induced pluripotent stem cells (iPSCs) and organ‑on‑chip technologies, to better understand disease mechanisms and accelerate therapeutic discovery. This PDRA post focuses on the development and characterisation of iPSC‑derived adipose tissue models and their integration into multi‑tissue platforms.

The Role

The successful candidate will play a central role in contributing to the generation of biomimetic, immunocompetent adipose tissue constructs derived from human iPSCs. Working closely with stem cell biologists, immunologists, and bioengineers across the MIMIC consortium, the PDRA will:

• Develop and optimise iPSC‑derived adipocyte differentiation protocols 
• Generate 3D adipose tissue organoids incorporating stromal, endothelial, and immune cell populations
• Perform in‑depth molecular, phenotypic and metabolic characterisation of adipose models
• Investigate inflammatory and metabolic dysfunction relevant to MASLD
• Contribute to multi‑organ integration, i.e. adipose–liver–gut cross‑talk 
• Support benchmarking of in‑vitro findings against clinical and patient‑derived data

This role provides an exceptional opportunity to work at the cutting edge of human disease modelling, immunometabolism, and regenerative medicine within a large, well‑funded collaborative programme.

About you

You will hold a PhD/DPhil or equivalent a relevant discipline along with:

• Strong hands‑on experience of stem cell-derived models
• Demonstrated expertise in adipose tissue biology and adipocyte differentiation
• Experience with 3D cell culture, organoid systems, or co‑culture models
• Solid grounding in molecular and cellular biology techniques 
• Ability to work both independently and collaboratively within a large interdisciplinary programme

Informal enquiries are welcome and may be directed to: Jaswinder Sethi (j.sethi@soton.ac.uk). Please note that applications sent only to this email address will not be accepted.

What we offer 

• An exciting post within a high‑profile UKRI‑funded research programme
• Access to world‑class facilities and international collaborators
• Strong mentorship and career development, including training and conference support
• Opportunities for collaboration, secondments, and interdisciplinary skills development
• A generous holiday allowance as well as additional university closure days
• A vibrant, inclusive, and supportive research environment

Closing Date: 01 Sep 2026

Section: Education, Research & Enterprise

Salary: £36,636 to £41,064 Per Annum
Full Time Fixed Term for 24 months

SCTU is a leading UK academic CTU located within the state-of-the-art Centre for Cancer Immunology building at Southampton General Hospital. Southampton Clinical Trials Unit (SCTU) | University of Southampton

SCTU is a UKCRC registered CTU and is core-funded by Cancer Research UK (CRUK) together with funding from the National Institute for Health and Care Research (NIHR) via the Biomedical Research Centre (BRC) and Research Support Service (RSS). 

SCTU has expertise in the design, conduct and publication of clinical trials and other well-designed studies from first-in-human phase I to practice changing phase III trials to large early diagnosis observational studies with rich translational data. Managing a growing portfolio (75% cancer, 25% non-cancer) that covers the complete spectrum of clinical practice, from primary care through to tertiary referral medicine, including pan-cancer experimental therapeutics, surgery, radiotherapy and early diagnosis. Undertaking multi-centre early and late phase clinical trials, we work nationally and internationally to create the evidence for patient benefit that will directly influence routine clinical practice in the NHS and overseas. 

As part of the CRUK and NIHR infrastructure we have close working relationships with our partners, including the Southampton Experimental Cancer Research Centre, NIHR BRC & RSS, University Hospital Southampton, the Centre for Cancer Immunology discovery community and CRUK Centres and Institutes across the UK, with an increasing number of international collaborations. 

The Senior Trials Manager will lead the relevant portfolio team to ensure effective delivery of the overall strategy and delivery priorities for SCTU. This will include resource management, oversight of financial management, new trial development, grant applications, and the ability to anticipate and consider potential issues or opportunities which could affect delivery and growth of the relevant portfolio.

The appointed person must have proven experience of running clinical trials, with a focus on multistakeholder studies collecting patient samples for analysis, and including new trial development.

This position is full time, or part time (minimum 0.6FTE), fixed term for 24 months. 

The employing organisation is the University of Southampton which offers a competitive salary, pension scheme, generous holiday entitlement and other benefits. 

For informal queries please contact Nicole Keyworth, Portfolio Lead, on n.e.keyworth@soton.ac.uk

Closing Date: 31 Aug 2026

Section: Management, Specialist & Administrative

Salary: £46,049 to £58,225 per annum
Full Time Fixed Term for 24 months

We are looking to recruit a Teaching Fellow in Anatomical Sciences to join our committed and enthusiastic team of anatomists and technical staff in our goal to provide the highest quality student experience. This post is based at Southampton General Hospital in the Centre for Learning Anatomical Sciences (CLAS) which comprises a large Anatomical Sciences Laboratory. We are part of the School of Primary Care, Population Sciences and Medical Education in the Faculty of Medicine and we have close interdisciplinary links with other members of the faculty and wider University. 

The University of Southampton is a global centre for excellence in education and research and a founding member of the Russell Group. The Centre for Learning Anatomical Sciences (CLAS) is part of the larger Medical Education group within the Faculty of Medicine and we benefit from a resource-rich creative environment and the close proximity of our clinical colleagues.

Our principal role is to develop and deliver human anatomy teaching and learning for undergraduates. Teaching areas include gross anatomy, microanatomy, developmental anatomy and neuroanatomy. Members of academic staff also have curriculum management and development roles in the Faculty and wider University.

Anatomy is taught through prosected specimens which we create in house through the generous donation of members of the public. Our catchment area for donations is the South East of England. Central to our method of delivery is a student-centred approach providing students with a resource-rich environment in which to study. Students undertake a range of activities using high quality bespoke prosected specimens, plastinated and museum specimens, plastic models, bones, imaging material and eLearning packages.

Our team comprises the Director of the Centre, 1 Principal Teaching Fellow, 5 Teaching Fellows, Technical Manager and Deputy and 2 Anatomy Laboratory Technicians. Our work is supported by the CLAS administrator.

The successful candidate will have a good knowledge of anatomy and its sub-disciplines, experience in demonstrating anatomy in practical classes and be enthusiastic and flexible in supporting staff in the delivery of undergraduate and postgraduate teaching. We are looking for someone that is keen to participate fully in the intellectual and academic activities of a lively and committed department which values collegiality highly with the aim to deliver the highest quality student experience.

We are seeking to appoint a Medical or Anatomy graduate. The successful candidate will ideally have had experience working within a human anatomy morbid facility. You will be an excellent team player and have a good understanding of the Human Tissue Act. Experience working in a medical school is desirable.

For additional information/informal enquiries before submitting your application, contact Dr Skantha Kandiah, Director of the Centre for Learning Anatomical Sciences and Head of Medical Education at S.S.Kandiah@soton.ac.uk 

Please include a covering letter and full CV in your application. Only applications made online through the University system before the deadline will be considered.

If you have previously applied for this role, a new application is not required.

Closing Date: 12 Aug 2026

Section: Education, Research & Enterprise

Salary: £36,636 to £44,746 per annum
Full Time Permanent

The NIHR Maternity Disparities Consortium is a £50 million national initiative bringing together a diverse range of organisations with expertise in research, capacity development and working with people and communities to deliver a step change in maternity outcomes and developing future research leaders in this area of need. The research carried out by the consortium will focus on inequalities before, during and after pregnancy.

The postholder will join the Preconception and Interpregnancy Health theme, which is evaluating a new system-wide blueprint for preconception and interpregnancy care and support. Working within a multidisciplinary team, you will undertake a mixed-methods evaluation, using qualitative and quantitative research to understand the blueprint’s implementation, effectiveness and impact on maternity outcomes.

You will play a key role in designing and delivering research, collecting and analysing data, publishing findings, working closely with NHS, community and third-sector partners, and contributing to knowledge exchange activities. The role offers excellent opportunities to develop your research profile, build collaborative networks, and contribute to improving outcomes for women and families, particularly those from underserved communities.

This is a full-time (1.0 FTE) fixed-term appointment until 31 May 2028, in the first instance. Subject to NIHR review and funding, there may be opportunities for elements of the research programme to continue beyond this date.

For an informal discussion about the role, please contact Dr Danielle Schoenaker (D.Schoenaker@soton.ac.uk).

Closing Date: 11 Aug 2026

Section: Education, Research & Enterprise

Salary: £36,636 to £44,746
Full Time Fixed Term (until 31/05/2028)

Due to expansion, we currently have a vacancy for a Senior Trial Manager to join the existing cancer portfolio team. The Senior Trial Manager will be responsible for the oversight of trials ensuring they are delivered according to required standards, time and budget. This is a senior post within the CTU with advisory, leadership, engagement, and line management responsibilities.

The appointed Senior Trial Manager will work specifically on a single trial developing SCTU expertise into clinical collaboration opportunities with industry partners, where an academically sponsored trial will result is supporting MHRA drug licencing, which aims to fulfil faster movement from research to patient access.

The successful candidate will have significant experience of trial management gained through working on interventional clinical trials, including experience of IMP management, and have excellent knowledge of legislation, regulation and governance environments relating to clinical trials. The Senior Trial Manager will be required to work with multiple stakeholders so must have an excellent communication style and experience of matrix management, as well as the ability to multi-task, meet deadlines and be a good leader and line manager. Experience of regulatory affairs including submitting drugs for licencing would be an advantage.

SCTU is a leading UK academic CTU located within the state-of-the-art Centre for Cancer Immunology building within the University of Southampton, based at Southampton General Hospital. Having patient benefit at the heart of everything it does, SCTU is a UKCRC registered CTU and is core-funded by Cancer Research UK (CRUK) together with funding from the National Institute for Health and Care Research (NIHR) via the Biomedical Research Centre (BRC) and Research Support Service (RSS). Southampton Clinical Trials Unit (SCTU) | University of Southampton

The CTU is part of a strong research environment in Southampton which includes the Experimental Cancer Medicine Centre, Clinical Research Facility and strong links with The University Hospital Southampton NHS Foundation Trust NHS R&D Management.

The employing organisation is the University of Southampton which offers a competitive salary, pension scheme and other benefits. The post is offered on a two year full-time fixed term contract in the first instance with the possibility of an extension; part time may be considered at 0.8 FTE. This will be a hybrid role with a requirement to work in the office in Southampton at least 60% of contracted hours. Working at the University of Southampton provides many benefits: Check out the staff benefits page.

For an informal discussion please contact Andrea Corkhill, Head of Trial Management, Oncology akc@soton.ac.uk

Please note, this advert may close early, so early applications are advised.

Closing Date: 17 Aug 2026

Section: Management, Specialist & Administrative

Salary: £46,049 to £58,225 per annum
Full Time Fixed Term for 2 years