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CRUK ECRIN-M3 Data Manager in B-cell Malignancies

Cancer Sciences

Location:  Southampton General Hospital
Salary:   £30,942 to £33,797 per annum
Full Time Fixed Term (until 30/06/2025)
Closing Date:  Friday 07 August 2020
Interview Date:   Friday 04 September 2020
Reference:  1276720CM

Applications are invited for a CRUK Data Manager position to join the CRUK accelerator programme ‘Early Cancer Research Initiative Network on Monoclonal B-cell Lymphocytosis (ECRIN-M3) awarded to Dr Francesco Forconi.

For personalised medicine to become a clinical reality we must meaningfully integrate and interrogate patient multi-dimensional data. We can produce a learning health system in which high dimensional data is routinely integrated into the clinical arena and iteratively interrogated to discover new prognostic and stratification signatures and refine those known. 

You will lead in a new clinical research study on the management of the clinical and research data of monoclonal B-cell lymphocytosis (MBL) and other early-stage B cell malignancies, working with data specialists in the Clinical Informatics Research unit and with an expanding team of clinicians and scientists with a strong grounding in cancer B-cell immunology, genomics, molecular/cellular biology and bioinformatics at the School of Cancer Sciences. You will use an Electronic Case Report Form ALEAS and the BC Platforms data warehouse incorporating medical records and high-dimensional biomedical data, as well as applying the latest trans-disciplinary data analysis techniques to refine phenotypic, genetic and functional marker to improve clinical decision-making. You will ensure the collection and validation of clinical and biological data flowing from recruiting sites into your platforms. You will coordinate the study by interacting directly with local ECRIN-M3 team members, research assistants and nurses, and with international collaborators, including those from Spain and Italy involved in the programme.

You will be an enthusiastic and well-motivated investigator capable of developing your research project as well as a good team-player with excellent communication skills, working in a fertilising environment of clinicians and scientists with a strong grounding in cancer B-cell immunology, genomics, molecular/cellular biology and bioinformatics. You will design new models of disease progression from the very early stages (early cancer) to overt B-cell leukaemias and lymphomas. You will be expected to contribute to the development and enhancement of the B-cell group within the School of Cancer Sciences, nationally and internationally.

The successful candidate will have a PhD degree or equivalent EU qualification and experience,  with deep knowledge of medical statistics. Knowledge on prognostic scores in mature B-cell malignancies, including chronic lymphocytic leukaemia and indolent B-cell lymphomas are desirable. Applications from EU and international candidates are welcome.

This post will be based within the Cancer Research UK Centre and Centre for Cancer Immunology at the Southampton General Hospital campus, occupying modern, well-equipped, purpose-built laboratories, with support from clinical and laboratory-based colleagues. 

Additional details about the School of Cancer Sciences can be found at https://www.southampton.ac.uk/medicine/academic_units/academic_units/cancer_sciences.page

The position is funded by Cancer Research UK and is full-time, fixed-term to June 2025 in the first instance with full duration expected to be 60 months, subject to continued funding . 

For an informal discussion or to arrange a visit, please contact Dr Francesco Forconi (f.forconi@soton.ac.uk) or Professor James Batchelor (J.Batchelor@soton.ac.uk). 

Application Procedure: 

You should submit your completed online application form at https://jobs.soton.ac.uk. The application deadline will be midnight on the closing date stated above. If you need any assistance, please call Kate Pounds (Recruitment Team) on +44 (0) 23 8059 5456. Please quote reference 1276720CM on all correspondence.


The closing date for this job opportunity has now passed, and applications are no longer being accepted for this position

Further details:

We aim to be an equal opportunities employer and welcome applications from all sections of the community. Please note that applications from agencies will not be accepted unless indicated in the job advert.


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