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Marie Sklodowska Curie Fellow ITN

Chemical Biology, Diagnostics & Therapeutics

Location:  Highfield Campus
Salary:   £36,718 to £48,937 per annum, subject to bi-annual review due to exchange rates
Full Time Fixed Term for 3 years
Closing Date:  Tuesday 16 March 2021
Interview Date:   To be confirmed
Reference:  1336021EB

We are seeking to recruit two enthusiastic Early Stage Researchers / PhD students as part of the H2020 MSCA Training Network “Oligonucleotides for Medical Applications - OLIGOMED”. You will join an international cohort of 15 ESR fellows researching key topics in the use of synthetic oligonucleotides (ONs) for medical applications, starting in June 2021.

Modified ONs are considered the next generation drugs in personalised medicine. We are developing a platform technology which involves design and synthesis of modified ONs, optimisation of cell targeting and uptake, and medicinal studies in cancer, Huntingdon's Disease and cardiovascular diseases. To achieve this, we have a dedicated European network comprising of academic research teams in Southampton (lead), Stockholm, Gent, Bordeaux, Marseille, Udine and Cambridge, and includes industrial partners in London, Warsaw, Stockholm and Goteborg, as well as clinical partners in Southampton and Stockholm.

The two projects cover:

i) the development and optimisation of protocols for a modular ON self-assembly system, which combines the membrane nanopores with adjustable targeting modules (to target cancer cells specifically) and therapeutic units (to enhance cancer cell killing).

ii) the development ONs for highly selective targeting of the cMYC mRNA IRES, thereby avoiding potential confounding effects of broader translational inhibition.

More specific details can be found in the advertisements of the individual PhD projects for ESR1 (project i)) and ESR2 (project ii)) and on our dedicated OLIGOMED website.

In order to be considered for this post, please also complete the postgraduate application process via:

To be successful you must have a BSc or MSc or equivalent professional qualifications and experience in Chemistry, Chemical Biology or related field. At the time of recruitment (i.e. first date of employment), you must not have resided or carried out your main activity (work, studies, etc…) in the UK for more than 12 months in the 3 years immediately prior to recruitment under this project and you must be eligible for home/EU (non-overseas) fees at the University of Southampton. Compulsory national service and/or short stays such as holidays are not taken into account. At the time of recruitment, you must not yet have been awarded your doctorate and must be in the first 4 years (full-time equivalent) of your research career.  

Equality, diversity and Inclusion is central to the ethos in Chemistry. We particularly encourage women, Black, Asian and minority ethnic (BAME), LGBT and disabled applicants to apply for this position. In recognition of our continued commitment to improving equality for women in science we were awarded an Athena SWAN Silver award in 2014 a and a second Silver award in 2017. Chemistry gives full consideration to applicants that wish to work flexibly including part-time and due consideration will be given to applicants who have taken a career break. The University has a generous maternity policy* and onsite childcare facilities. For further information please visit

The University of Southampton is in the top 1% of world universities and in the top 10 of the UK’s research-intensive universities. The University of Southampton is committed to sustainability and being a globally responsible university and has recently been awarded the Platinum EcoAward. Our vision is to embed the principles of sustainability into all aspects of our individual and collective work, integrating sustainable development into our business planning, policy-making, and professional activities. This commits all of our staff and students to take responsibility for managing their activities to minimise harm to the environment, whether this is through switching off non-essential electrical equipment or using the recycling facilities.

 *subject to qualifying criteria

For informal enquiries contact Dr Eugen Stulz (

Application procedure:

You should submit your completed online application form at The application deadline will be midnight on the closing date stated above. If you need any assistance, please email or call Hannah Farrance (Recruitment Team) on +44 (0) 23 8059 2507. Please quote reference 1336021EB on all correspondence.

Please include a covering letter, full CV and 2 letters of recommendation in your application. 

Athena SWAN Silver Award holder: Chemistry



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We aim to be an equal opportunities employer and welcome applications from all sections of the community. Please note that applications from agencies will not be accepted unless indicated in the job advert.

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